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Section One: FUEL METABOLISM 1: Metabolic Fuels and Dietary Components 2: The Fed or Absorptive State 3: Fasting Section Two : CHEMICAL AND BIOLOGICAL FOUNDATIONS OF BIOCHEMISTRY 4: Water, Acids, Bases, and Buffers 5: Structures of the Major Compounds of the Body 6: Amino Acids in Proteins 7: Structure-Function Relationships in Proteins 8: Enzymes as Catalysts 9: Regulation of Enzymes 10: Relationship between Cell Biology and Biochemistry 11: Cell Signaling by Chemical Messengers Section Three: GENE EXPRESSION AND THE SYNTHESIS OF PROTEINS 12: Structure of the Nucleic Acids 13: Synthesis of DNA 14: Transcription: Synthesis of RNA 15: Translation: Synthesis of Proteins 16: Regulation of Gene Expression 17: Use of Recombinant DNA Techniques in Medicine 18: The Molecular Biology of Cancer Section Four: FUEL OXIDATION AND THE GENERATION OF ATP 19: Cellular Bioenergetics: ATP and O2 20: Tricarboxylic Acid Cycle 21: Oxidative Phosphorylation and Mitochondrial Function 22: Generation of Adenosine Triphosphate from Glucose: Glycosis 23: Oxidation of Fatty Acids and Ketone Bodies 24: Oxygen Toxicity and Free Radical Injury 25: Metabolism of Ethanol Section Five: CARBOHYDRATE METABOLISM 26: Basic Concepts in the Regulation of Fuel Metabolism by Insulin, Glucagon, and Other Hormones 27: Digestion, Absorption, and Transport of Carbohydrates 28: Formation and Degradation of Glycogen 29: Pathways of Sugar Metabolism: Pentose Phosphate Pathway, Fructose, and Galactose Metabolism 30: Synthesis of Glycosides, Lactose, Glycoproteins, and Glycolipids 31: Gluconeogenesis and Maintenance of Blood Glucose Levels Section Six: LIPID METABOLISM 32: Digestion and Transport of Dietary Lipids 33: Synthesis of Fatty Acids, Triacylglycerols, and the Major Membrane Lipids 34: Cholesterol Absorption, Synthesis, Metabolism, and Fate 35: Metabolism of the Eicosanoids 36: Integration of Carbohydrate and Lipid Metabolism Section Seven: NITROGEN METABOLISM 37: Protein Digestion and Amino Acid Absorption 38: Fate of Amino Acid Nitrogen: Urea Cycle 39: Synthesis and Degradation of Amino Acids 40: Tetrahydrofolate, Vitamin B12, and S-Adenosylmethionine 41: Purine and Pyrimidine Metabolism 42: Intertissue Relationships in the Metabolism of Amino Acids Section Eight: TISSUE METABOLISM 43: Actions of Hormones That Regulate Fuel Metabolism44: The Biochemistry of the Erythrocyte and Other Blood Cells 45: Blood Plasma Proteins, Coagulation and Fibrinolysis 46: Liver Metabolism 47: Metabolism of Muscle at Rest and During Exercise 48: Metabolism of the Nervous System 49: The Extracellular Matrix and Connective Tissue Appendix: Answers to Review Questions Index